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位置: 首页> 品牌> Sigma-Aldrich> Anti-Nup96 Antibody, clone 4H5

Anti-Nup96 Antibody, clone 4H5

品牌
Sigma-Aldrich
货号
MABE1039
规格纯度
clone 4H5, from rat
价格
4513.21 *本价格含增值税费
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数量
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半岛bd体育手机客户端 名称:
Anti-Nup96 Antibody, clone 4H5
Nuclear pore complex protein Nup98-Nup96, Nuclear pore complex protein Nup98, 98 kDa nucleoporin, Nucleoporin Nup98, Nup98, Nuclear pore complex protein Nup96, 96 kDa nucleoporin, Nucleoporin Nup96, Nup96, Nup96
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

The murine gene Nup98 (Gene ID 269966; also known as AI849286, 4732457F17) encodes the 1816-amino acid nuclear pore complex protein Nup98-Nup96 (UniProt Q6PFD9), which is posttranslationally autocleaved between aa 800 and 801 to form Nup98 (aa 1-800) and Nup96 (aa 801-1816). The nuclear pore complex (NPC) acts as a passageway for nucleocytoplasmic transport. The core structure of the NPC is maintained by the Nup93-205 complex sandwiched between the supporting structures of the Nup107-160 complex on the nuclear and cytoplasmic faces of the pore. Nup96 is a component of the Nup107-160 complex, the largest subunit of the NPC. Nup96 knockout is reported to be fatal in mice and Nup96(+/-) mice with low levels of Nup96 display impaired immune response and are highly susceptible to viral infection.

特异性

Reacts with Nup98-Nup96 precursor (isoforms 1, 2, and 6), nucleoporin Nup96 (isoform 5), but not nucleoporin Nup98 (isoform 3).

免疫原

GST-tagged recombinant protein corresponding to mouse Nup96 near the N-terminus.
Epitope: Near N-terminus.

应用

Research Sub Category
Nuclear Receptors
Anti-Nup96 Antibody, clone 4H5 is an antibody against Nup96 for use in Western Blotting and Immunocytochemistry.
Research Category
Epigenetics & Nuclear Function
Western Blotting Analysis: A representative lot detected Nup96 in NIH/3T3 cells (Mizuguchi, C., et al. (2010). Hybridoma. 29(6):551-553).
Immunocytochemistry Analysis: A representative lot detected Nup96 in NIH/3T3 cells (Mizuguchi, C., et al. (2010). Hybridoma. 29(6):551-553).

质量

Evaluated by Western Blotting in NIH/3T3 cell lysate.

Western Blotting Analysis: 2.0 ?g/mL of this antibody detected Nup96 in 10 ?g of NIH/3T3 cell lysate.

目标描述

~120 kDa observed

外形

Purified rat monoclonal IgG2aκ antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Format: Purified
Protein G Purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

其他说明

Concentration: Please refer to lot specific datasheet.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss 32160702

半岛bd体育手机客户端 性质

质量水平 100
生物来源 rat
抗体形式 purified antibody
antibody product type primary antibodies
克隆 4H5, monoclonal
species reactivity mouse
technique(s) immunocytochemistry: suitable
western blot: suitable
同位素/亚型 IgG2aκ
NCBI登记号 NP_001274093
UniProt登记号 Q6PFD9
运输 wet ice

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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