半岛bd体育手机客户端 说明
一般描述
Myelin transcription factor 1-like (Myt1L) is a zinc finger protein belonging to the myelin transcription factor 1 family. It influences the expression of genes involved in the proliferation and differentiation of oligodentrocytes in the developing central nervous system. Myt1L may contribute to the silencing of its target genes by recruiting Sin3B that binds to and enhances the activity of HDAC. Several studies have implicated Myt1L in the pathogenesis of complex psychiatric diseases such as schizophrenia, major depressive disorder, and bipolar disorder.
免疫原
GST-tagged recombinant protein corresponding to human MyT1L.
应用
Detect the MyT1L protein using this Anti-MyT1L, clone 20B4.1 validated for use in WB & IHC.
Immunohistochemistry Analysis: A 1:10-1:50 dilution from a representative lot detected MyT1L in human pons, mouse frontal cortex, and mouse hippocampus tissues.
Research Category
Neuroscience
Research Sub Category
Developmental Neuroscience
质量
Evaluated by Western Blot in mouse E17 spinal cord tissue lysate.
Western Blot Analysis: A 1:1.000 dilution of this antibody detected MyT1L on 10 ?g of mouse E17 spinal cord tissue lysate.
目标描述
~170 kDa observed. Uniprot describes three isoforms at 21, 126, and 133 kDa
外形
Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Format: Purified
Protein G Purified
储存及稳定性
Stable for 1 year at 2-8°C from date of receipt.
分析说明
Control
Mouse E17 spinal cord tissue lysate
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
半岛bd体育手机客户端 性质
| 质量水平 | 100 |
| 生物来源 | mouse |
| 抗体形式 | purified immunoglobulin |
| antibody product type | primary antibodies |
| 克隆 | 20B4.1, monoclonal |
| species reactivity | mouse, human |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| 同位素/亚型 | IgG1κ |
| NCBI登记号 | NP_055840 |
| UniProt登记号 | Q9UL68 |
| 运输 | wet ice |
| Gene Information | human ... MYT1L(23040) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
