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位置: 首页> 品牌> Sigma-Aldrich> Anti-LIBS2 epitope (Integrin beta3 subunit) Antibody, clone ab62

Anti-LIBS2 epitope (Integrin beta3 subunit) Antibody, clone ab62

品牌
Sigma-Aldrich
货号
MABT27
规格纯度
clone ab62, from mouse
价格
6022.61 *本价格含增值税费
促销
服务
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  • 增值税票
数量
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半岛bd体育手机客户端 名称:
Anti-LIBS2 epitope (Integrin beta3 subunit) Antibody, clone ab62
LIBS2 domain, Integrin, Integrin alphaVbeta3, LIBS2 epitiope
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

The integrin family of cell adhesion receptors consists of at least 16 membrane-associated heterodimers, composed of an alpha and beta subunit that associate in a non-covalent manner. The involvement of integrins in vascular proliferation, adhesion, and wound repair has been well documented. The adhesion receptor, integrin alphaVbeta3, appears to be selectively expressed on growing blood vessels and has been identified as a marker of angiogenic vascular tissue.
Clone Ab62 is a monoclonal antibody that specifically recognizes the LIBS2 epitope in the C-terminal region of the extracellular domain of the beta3 subunit (Wiberzbicka-Patynowski, I., et al. (1999). JBC. 274(53):37809-37814).

特异性

This antibody recognizes the LIBS2 epitope in the C-terminal region of the extracellular domain of the beta3 subunit of integrins.

免疫原

Human GPIIa-IIIb purified from platelets
Epitope: LIBS2 epitope in the C-terminal region of the extracellular domain of the beta3 subunit of integrins.

应用

Research Category
Cell Structure
Research Sub Category
Integrins
Anti-LIBS2 epitope (Integrin beta3 subunit) Antibody, clone ab62 is an antibody against LIBS2 epitope (Integrin beta3 subunit) for use in WB, FC.
Flow Cytometry Analysis: A previous lot was used by an independent laboratory in FC (Ginsberg, M., et al. (1990). Blood. 76:2017-2023.)

质量

Evaluated by Western Blot in human platelets cell lysate.

Western Blot Analysis: 0.5 ?g/mL of this antibody detected LIBS2 domain of integrin beta3 subunit in 10 ?g of human platelets cell lysate.

目标描述

~110 kDa observed in human platelets.
Other MW bands may vary or may be observed depending on lysate used and if the LIBS2 epitope is present in other proteins.

外形

Format: Purified
Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Protein G Purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

分析说明

Control
Human platelets cell lysate

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss 32160702
NACRES NA.41

半岛bd体育手机客户端 性质

质量水平 100
生物来源 mouse
抗体形式 purified immunoglobulin
antibody product type primary antibodies
克隆 ab62, monoclonal
species reactivity human
technique(s) flow cytometry: suitable
western blot: suitable
同位素/亚型 IgG2aκ
运输 wet ice

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

Sigma-Aldrich

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