Anti-ISL-1 Antibody, clone 16E8.1

半岛bd体育手机客户端 说明

一般描述

Islet-1 (ISL-1) is a transcription factor that plays an important role in the embryogenesis of pancreatic islets of Langerhans. It is expressed in subsets of neurons of the adrenal medulla and dorsal root ganglion, inner nuclear and ganglion cell layers in the retina, the pineal and some regions of the brain. In mouse embryos, a deficiency of this gene fail to undergo neural tube motor neuron differentiation. More recently it has been identified as a marker for a cardiac progenitor cell lineage that is capable of differentiating into all 3 major heart cell types: cardiomyocytes, smooth muscle and endothelial cell lineages.

免疫原

GST-tagged linear peptide corresponding to Human ISL-1.

应用

Evaluated by Immunohistochemistry in both human cerebellum and rat hippocampal tissue. Immunohistochemsitry Analysis: A 1:1000 dilution of this antibody detected ISL-1 in both human cerebellum and rat hippocampal tissue.
This Anti-ISL-1 Antibody, clone 16E8.1 is validated for use in Western Blotting and Immunohistochemistry (Paraffin) for the detection of ISL-1.
Research Sub Category
Pluripotent & Early Differentiation
Research Category
Stem Cell Research

质量

Evaluated by Western Blot in a K562 cell lysate. Western Blot Analysis: A 1μg/ml (1:1000) dilution of this antibody detected ISL-1 in a K562 cell lysate.

目标描述

~ 40 kDa observed

外形

Format: Purified
Purified mouse monoclonal IgG2bκ supernatant in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Protein G Purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss	32160702
NACRES	NA.41

半岛bd体育手机客户端 性质

质量水平	100
生物来源	mouse
抗体形式	purified immunoglobulin
antibody product type	primary antibodies
克隆	16E8.1, monoclonal
species reactivity	human, rat
浓度	1 mg/mL
technique(s)	immunohistochemistry: suitable (paraffin) western blot: suitable
同位素/亚型	IgG2bκ
NCBI登记号	NP_002193
UniProt登记号	P61371
运输	wet ice
Gene Information	human ... ISL1(3670)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable