Anti-APAF1 antibody produced in chicken

半岛bd体育手机客户端 说明

免疫原

Immunogen Sequence: GI # 32483361, sequence 307-388
Recombinant apoptotic protease activating factor isoform d

应用

Anti-APAF1 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

生化/生理作用

Apoptotic protease activating factor 1 is a human homolog ofC. elegansCED-4 gene and is a key regulator gene of apoptosis. It acts as a central component of the intrinsic pathway of apoptosis. Loss of APAF-1 expression is involved with chemorefractory malignant melanoma and neuronal cell differentiation. Over expression of this gene is related to an undifferentiated state in the testicular germ cell tumor (TGCT) pathway and is involved in carcinogenesis of germ cell tumors. APAF-1, when bound to cytochrome c, may trigger the activation of caspase-3 leading to apoptosis.

外形

Solution in phosphate buffered saline containing 0.02% sodium azide.

基本信息

MDL编号	MFCD02095846
NACRES	NA.41

半岛bd体育手机客户端 性质

生物来源	chicken
偶联物	unconjugated
抗体形式	affinity isolated antibody
antibody product type	primary antibodies
克隆	polyclonal
形式	buffered aqueous solution
species reactivity	human, mouse
manufacturer/tradename	Genway 15-288-21169
technique(s)	western blot: suitable
NCBI登记号	NP_863658.1
UniProt登记号	O14727
运输	wet ice
储存温度	?20℃
Gene Information	human ... APAF1(317)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)