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Akt Inhibitor XII, Isozyme-Selective, Akti-2-Calbiochem

品牌
Sigma-Aldrich
货号
124029
规格纯度
The Akt Inhibitor XII, Isozyme-Selective, Akti-2 controls the biological activity of Akt. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
价格
4923.29 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
- +
半岛bd体育手机客户端 名称:
Akt Inhibitor XII, Isozyme-Selective, Akti-2-Calbiochem
1-((2-(4-((4-(2,3-Dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinyl)methyl)phenyl)-3-phenyl-6-quinoxalinyl)carbonyl)-4-methyl-piperazine, 3HCl and, 1-((3-(4-((4-(2,3-Dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinyl)methyl)phenyl)-2-phenyl-6-quinoxalinyl
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

A cell-permeable Akti-1/2- (Cat. No. 124018) derived allosteric inhibitor pair (1:1 regioisomeric mixture) with much improved aqueous solubility (10 mg/ml in a pH 7.4 saline) and Akt2 selectivity (IC50= 805 nM for Akt2, >10 ?M for Akt1/3, and >50 ?M for PKA/PKC/SGK). The inhibition is PH domain-dependent and non-competitive with ATP.
A cell-permeable Akti-1/2- (Cat. No. 124018) derived allosteric inhibitor pair (1:1 regioisomeric mixture) with much improved aqueous solubility (10 mg/ml in a pH 7.4 saline) and Akt2 selectivity (IC50= 805 nM for Akt2, >10 ?M for Akt1/3, and >50 ?M for PKA/PKC/SGK). The inhibition is PH domain-dependent and non-competitive with ATP.

包装

2 mg in Glass bottle
Packaged under inert gas

警告

Toxicity: Standard Handling (A)

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式 C39H39N7O2· 3HCl
分子量 747.16

半岛bd体育手机客户端 性质

质量水平 100
测定 ≥97% (mixture of regioisomers, HPLC)
形式 solid
manufacturer/tradename Calbiochem?
储存条件 OK to freeze
desiccated (hygroscopic)
protect from light
颜色 yellow
溶解性 DMSO: 25 mg/mL
water: 50 mg/mL
运输 ambient
储存温度 2-8℃

安全信息

储存分类代码 11 - Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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