半岛bd体育手机客户端 说明
一般描述
A cell-permeable Akti-1/2- (Cat. No. 124018) derived allosteric inhibitor pair (1:1 regioisomeric mixture) with much improved aqueous solubility (10 mg/ml in a pH 7.4 saline) and Akt2 selectivity (IC50= 805 nM for Akt2, >10 ?M for Akt1/3, and >50 ?M for PKA/PKC/SGK). The inhibition is PH domain-dependent and non-competitive with ATP.
A cell-permeable Akti-1/2- (Cat. No. 124018) derived allosteric inhibitor pair (1:1 regioisomeric mixture) with much improved aqueous solubility (10 mg/ml in a pH 7.4 saline) and Akt2 selectivity (IC50= 805 nM for Akt2, >10 ?M for Akt1/3, and >50 ?M for PKA/PKC/SGK). The inhibition is PH domain-dependent and non-competitive with ATP.
包装
2 mg in Glass bottle
Packaged under inert gas
警告
Toxicity: Standard Handling (A)
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
经验(实验)分子式 | C39H39N7O2· 3HCl |
分子量 | 747.16 |
半岛bd体育手机客户端 性质
质量水平 | 100 |
测定 | ≥97% (mixture of regioisomers, HPLC) |
形式 | solid |
manufacturer/tradename | Calbiochem? |
储存条件 | OK to freeze desiccated (hygroscopic) protect from light |
颜色 | yellow |
溶解性 | DMSO: 25 mg/mL water: 50 mg/mL |
运输 | ambient |
储存温度 | 2-8℃ |
安全信息
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich