半岛bd体育手机客户端 说明
一般描述
A cell-permeable purine nucleoside compound that acts as a highly potent, tight binding transition state analog inhibitor of adenosine deaminase (ADA; Ki= 2.5 pM against partially purified human erythrocytes, and 0.48 to 9.1 nM against rat liver, rat intestine, rat hepatoma and human B cells). Reported to be an immunomodulator and exert selective toxicity towards lymphocytes.
包装
10 mg in Glass bottle
Packaged under inert gas
警告
Toxicity: Harmful & Carcinogenic / Teratogenic (E)
重悬
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
其他说明
Robak, T. 2007.Cancer Treat. Rev.33,710.
Klohs, W.D. and Kraker, A.J., 1992.Pharmacol. Rev.44,459.
Agarwal, R.P., et al. 1977.Biochem. Pharmacol.26,359.
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法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
经验(实验)分子式 | C11H16N4O4 |
分子量 | 268.27 |
半岛bd体育手机客户端 性质
质量水平 | 100 |
测定 | ≥98% (HPLC) |
形式 | solid |
manufacturer/tradename | Calbiochem? |
储存条件 | OK to freeze protect from light |
颜色 | white |
溶解性 | DMSO: 10 mg/mL, clear, colorless water: 50 mg/mL, clear, colorless |
运输 | ambient |
储存温度 | 2-8℃ |
SMILES string | O[C@@H]1CNC=NC2=C1N=CN2[C@@H]3O[C@H](CO)[C@H](O)C3[H] |
InChI | 1S/C11H16N4O4/c16-3-8-6(17)1-9(19-8)15-5-14-10-7(18)2-12-4-13-11(10)15/h4-9,16-18H,1-3H2,(H,12,13)/t6-,7+,8+,9+/m0/s1 |
InChI key | FPVKHBSQESCIEP-JQCXWYLXSA-N |
安全信息
象形图 | |
警示用语: | Danger |
危险声明 | H301 |
预防措施声明 | P264 - P270 - P301 + P310 - P405 - P501 |
危险分类 | Acute Tox. 3 Oral |
储存分类代码 | 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich