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位置: 首页> 品牌> Sigma-Aldrich> 4-(2-(Hex-5-ynamido)ethyl)benzenesulfonyl fluoride

4-(2-(Hex-5-ynamido)ethyl)benzenesulfonyl fluoride

品牌
Sigma-Aldrich
CAS
1375960-13-6
货号
914231
包装型号
规格纯度
≥95%
价格
3303.46 *本价格含增值税费
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半岛bd体育手机客户端 名称:
1375960-13-6
4-(2-(Hex-5-ynamido)ethyl)benzenesulfonyl fluoride
SFABP
Sulfonyl fluoride activity-based probe
DAS1
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

应用

4-(2-(Hex-5-ynamido)ethyl)benzenesulfonyl fluoride is an alkyne-functionalized sulfonyl fluoride activity-based probe (SFABP). Sulfonyl fluorides covalently modify reactive serines in addition to threonine, lysine, tyrosine, cysteine, and histidine residues in a context-specific manner. Activity-based probes are useful for the targeting, isolation, and identification of proteins. Furtermore, the alkyne handle on SFABP enables click chemistry-based incorpoation of azide tags, such as fluorophores or biotins, for visualization or enrichment and detection, respectively.

其他说明

Unbiased Mass Spectrometry Elucidation of the Targets and Mechanisms of Activity-Based Probes: A Case Study Involving Sulfonyl Fluorides

Sulfonyl fluorides as privileged warheads in chemical biology

Chemical Proteomics with Sulfonyl Fluoride Probes Reveals Selective Labeling of Functional Tyrosines in Glutathione Transferase

Sulfonyl Fluoride Analogues as Activity-Based Probes for Serine Proteases

Europium-Labeled Activity-Based Probe through Click Chemistry: Absolute Serine Protease Quantification Using 153Eu Isotope Dilution ICP/MS

基本信息

经验(实验)分子式 C14H16FNO3S
分子量 297.35

半岛bd体育手机客户端 性质

质量水平 100
测定 ≥95%
形式 powder
储存温度 ?20℃

安全信息

象形图 GHS07
警示用语: Warning
危险声明 H315 - H319
预防措施声明 P302 + P352 - P305 + P351 + P338
危险分类 Eye Irrit. 2 - Skin Irrit. 2
储存分类代码 11 - Combustible Solids

Sigma-Aldrich

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