半岛bd体育手机客户端 说明
应用
2-(3-But-3-ynyl-3H-diazirin-3-yl)-ethanol is used for chemical probe synthesis, this trifunctional building block contains a light-activated diazirine, alkyne tag, and hydroxyl synthetic handle. When appended to a ligand or pharmacophore through its hydroxyl linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.
其他说明
Technology Spotlight: Trifunctional Probe Building Blocks
Fluorescent Probes for Single-Step Detection and Proteomic Profiling of Histone Deacetylases
In Situ Proteome Profiling and Bioimaging Applications of Small-Molecule Affinity-Based Probes Derived From DOT1L Inhibitors
Reversible inhibitors arrest ClpP in a defined conformational state that can be revoked by ClpX association
Design and Synthesis of Minimalist Terminal Alkyne-Containing Diazirine Photo-Crosslinkers and Their Incorporation into Kinase Inhibitors for Cell- and Tissue-Based Proteome Profiling
基本信息
经验(实验)分子式 | C7H10N2O |
分子量 | 138.17 |
MDL编号 | MFCD29918290 |
半岛bd体育手机客户端 性质
质量水平 | 100 |
测定 | ≥95% |
形式 | liquid |
密度 | 1.08 g/mL |
储存温度 | ?20℃ |
SMILES string | OCCC1(N=N1)CCC#C |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich