半岛bd体育手机客户端 说明
一般描述
Potent and specific inhibitor of multiple ubiquitin hydrolases involved in pathways of intracellular protein modification and turnover. Useful for stabilizing endogenous orin vitrosynthesized ubiquitin-protein conjugates. May also be used to enhance or decrease the rates of ubiquitin-dependent degradation.
Potent and specific inhibitor of multiple ubiquitin hydrolases involved in pathways of intracellular protein modification and turnover. Useful for stabilizing endogenous orin vitrosynthesized ubiquitin-protein conjugates. May also be used to enhance or decrease rates of ubiquitin-dependent degradation.
包装
50 μg in Plastic ampoule
Please refer to vial label for lot-specific concentration.
生化/生理作用
Primary Target
multiple ubiquitin hydrolases involved in pathways of intracellular protein modification and turnover
Product does not compete with ATP.
Shown to inhibit the activity of Isopeptidase T (Cat. No. 419700) and Ubiquitin C-Terminal Hydrolase (Cat. No. 662090)
Reversible: no
Cell permeable: no
警告
Toxicity: Standard Handling (A)
外形
In 150 mM HCL.
重悬
Following reconstitution, aliquot and freeze (-20°C).
其他说明
Melandri, F., et al. 1996.Biochemistry35,12893.
Shaeffer, J.R. and Cohen, R.E. 1996.Biochemistry35,10886.
Pickart, C.M. and Rose, I.A. 1986.J. Biol. Chem.261,10210.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
半岛bd体育手机客户端 性质
质量水平 | 100 |
测定 | ≥95% (HPLC) |
形式 | liquid |
manufacturer/tradename | Calbiochem? |
储存条件 | OK to freeze |
溶解性 | DMSO: 50 mg/mL aqueous buffer: soluble |
运输 | ambient |
储存温度 | ?20℃ |
安全信息
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich