Anti-Bid Antibody

半岛bd体育手机客户端 说明

一般描述

Bid, a BH3 domain-containing proapoptotic Bcl-2 family member, is known to interact with Bcl-2 and Bax. It has been reported that Bid induces cytochrome c release from mitochondria following cleavage by caspase-8 in response to apoptotic stimuli transmitted through cell surface death receptors. The cytochrome c releasing activity of Bid was antagonized by Bcl-2. Mutation in the SH3 domain can diminish the cytochrome c releasing activity. In animal model studies, Bid-deficient mice are found resistant to the lethal effects of death factor signals relayed through Fas.

特异性

AB1735 recognizes Bid from human, mouse, rat and rabbit.

免疫原

Recombinant full length GST-tagged mouse Bid protein

应用

Research Category
Apoptosis & Cancer
Research Sub Category
BCL2 & Inhibition
Detect Bid using this Anti-Bid Antibody validated for use in WB, IP, IH.
Western blot: Recommended antibody dilution 1:3,000 to 1:6,000. Recognizes a band migrating at approximately 22 kDa corresponding to Bid.

Immunoprecipitation: Recommended antibody dilution 1:200

Immunohistochemistry: Recommended antibody dilution 1:1500

Optimal working dilutions must be determined by end user.

联系

Replaces: 04-438

外形

Whole serum without preservatives

储存及稳定性

Store at -20°C for up to 12 months.

法律信息

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss	32160702
NACRES	NA.41

半岛bd体育手机客户端 性质

生物来源	rabbit
质量水平	100
抗体形式	serum
antibody product type	primary antibodies
克隆	polyclonal
species reactivity	mouse, rabbit, rat, human
manufacturer/tradename	Chemicon?
technique(s)	immunohistochemistry: suitable immunoprecipitation (IP): suitable western blot: suitable
NCBI登记号	NM_001196.2 NM_197966.1 NM_197967.1
UniProt登记号	P55957
运输	dry ice

安全信息

储存分类代码	10 - Combustible liquids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable