半岛bd体育手机客户端 说明

特异性

Beta amyloid. Sequence is contained in the Amyloid beta-A4 protein amino acids 672-685 of human APP. The sequence is identical in the following other related proteins:

Cerebral vascular amyloid peptide) (CVAP) (Protease nexin-II) (PN-II) (APPI) (PreA4) [Contains: Soluble APP-alpha (S-APP-alpha); Soluble APP-beta (S-APP-beta); C99; Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); Gamma-CTF(59) (Gamma-secretase C-terminal fragment 59) (Amyloid intracellular domain 59) (AID(59)); Gamma-CTF(57) (Gamma-secretase C-terminal fragment 57).

100% homology in human, pig, sheep, rabbit, bovine, 78% identities (11/14), with 12/14 positives (85%) in rat and mouse beta amyloid containing proteins.

免疫原

Epitope: aa1-14 h beta-amyloid
Synthetic peptide that corresponds to the first 14 amino acids of the N-terminal sequence of beta-amyloid. {DAEFRHDSGYEVHH}

应用

Anti-Amyloid Antibody, β, aa1-14 h β-amyloid detects level of Amyloid & has been published & validated for use in WB, IH.
Research Category
Neuroscience
Research Sub Category
Neurodegenerative Diseases
Immunohistochemistry on formic acid treated histological sections. Suggested working dilution is >1:200. AB1510 will detect both cerebrovascular and core amyloid. Formic acid pretreatment (Vinters et al., 1988) involves deparaffinizing sections, follwed by incubation in a 99% formic acid solution (10-20 min), a tap water rinse (10 min), 0.3% H202 in tris-buffered saline, then 3.0% NGS (30 min) followed by primary antibody.

Immunoblotting of formic acid extracts of brain tissue.

ELISA, direct:≥ 1:1000

Optimal working dilutions must be determined by end user.

外形

Rabbit serum with 0.01% thimerosal.

储存及稳定性

Maintain at -20°C in undiluted aliquots for up to 12 months after date of receipt. Avoid repeated freeze/thaw cycles.

法律信息

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss	32160702
NACRES	NA.41

半岛bd体育手机客户端 性质

生物来源	rabbit
质量水平	100
抗体形式	serum
antibody product type	primary antibodies
克隆	polyclonal
species reactivity	human
manufacturer/tradename	Chemicon?
technique(s)	immunohistochemistry: suitable western blot: suitable
NCBI登记号	NM_000484.2 NM_201413.1 NM_201414.1
UniProt登记号	P05067
运输	dry ice
Gene Information	human ... APP(351)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable