PKC Inhibitor, EGF-R Fragment 651-658, Myristoylated-Calbiochem

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一般描述

Epidermal growth-factor receptor (EGF-R) conserved sequence which is identical to v-erbB (95-102). An N-terminal myristoylated membrane-permeable, reversible, and substrate competitive inhibitor that inhibits protein kinase C (IC₅₀= 5 ?M) in intact cells.
Epidermal growth-factor receptor (EGF-R) conserved sequence which is identical to v-ErbB (95-102). An N-terminal myristoylated membrane-permeable, reversible, and substrate competitive inhibitor of protein kinase C (IC₅₀= 5 ?M).

包装

500 μg in Plastic ampoule
Yes

生化/生理作用

Product does not compete with ATP.
Target IC₅₀: 5 ?M against protein kinase C
Reversible: yes
Primary Target
PKC
Cell permeable: yes

警告

Toxicity: Standard Handling (A)

序列

Myr-N-Arg-Lys-Arg-Thr-Leu-Arg-Arg-Leu-OH

外形

Supplied as a trifluoroacetate salt.

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.

其他说明

Ward, N.E., and O’Brian, C.A. 1993.Biochemistry32,11903.
O’Brian, C.A., et al. 1991.Invest. New Drugs9,169.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

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