Isoproterenol, Hydrochloride-CAS 51-30-9-Calbiochem

半岛bd体育手机客户端 说明

一般描述

Phenethylamine derivative. Selective β-adrenergic agonist that increases cytosolic cAMP. Promotes glycogen breakdown and causes bronchodilation. Increases Cl^-diffusion and potential difference in rabbit trachea cells through nitric oxide generation.
Phenethylamine derivative. Selective β-adrenergic agonist that stimulates adenylate cyclase activity. Promotes glycogen breakdown and causes bronchodilation. Increases Cl^–diffusion and potential difference in rabbit trachea cells through nitric oxide generation. Reported to activate MAP Kinase (ERK) by a Rap1 and B-Raf dependent process.

包装

100 mg in Plastic ampoule

生化/生理作用

Primary Target
β-adrenergic agonist
Product does not compete with ATP.
Reversible: no
Cell permeable: no

警告

Toxicity: Irritant (B)

重悬

Unstable in solution; reconstitute just prior to use.

其他说明

Schmitt, J.M., and Stork, P.J. 2000.J. Biol. Chem.275,25342.
Carmena, M.J., et al. 1997.Prostate33,46.
Takemura, H., et al. 1995.J. Pharmacol. Exp. Ther.274,584.
Kishimoto, I., et al. 1994.J. Biol. Chem.269,28300.
Macaulay, S.L., et al. 1994.Mol. Cell Biochem.141,27.
Yashiro, K., et al. 1994.J. Biochem.115,1040.
Ladenheim, R.G., et al. 1993.J. Neurochem.60,260.
von Zastrow, M., et al. 1993.J. Biol. Chem.268,763.
Mokhtari, A., et al. 1985.J. Cyclic Nucleotide Protein Phosphorylation Res.10,213.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式	C11H17NO3· xHCl
分子量	211.26 (free base basis)
MDL编号	MFCD00012603

半岛bd体育手机客户端 性质

质量水平	100
测定	≥99% (TLC)
形式	solid
manufacturer/tradename	Calbiochem?
储存条件	OK to freeze protect from light
颜色	white to off-white white
溶解性	ethanol: soluble water: soluble
运输	ambient
储存温度	10-30℃
InChI	1S/C11H17NO3.ClH/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8;/h3-5,7,11-15H,6H2,1-2H3;1H
InChI key	IROWCYIEJAOFOW-UHFFFAOYSA-N

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 2
闪点(F)	Not applicable
闪点(C)	Not applicable