InSolution SU6656-Calbiochem

半岛bd体育手机客户端 说明

一般描述

A potent inhibitor of Src-family protein tyrosine kinases. Inhibits Src (IC₅₀= 280 nM) as well as closely related kinases Fyn (IC₅₀= 170 nM), Yes (IC₅₀= 20 nM) and Lyn (IC₅₀= 130 nM). The inhibition is competitive with respect to ATP. Has only a trivial effect on Lck (IC₅₀= 6.88 ?M). Does not affect the activity of PDGF-β receptor kinase (IC₅₀>10 ?M) and IGF-1 receptor kinase (IC₅₀gt;20 ?M).

包装

500 μg in Plastic ampoule
Packaged under inert gas

生化/生理作用

Cell permeable: yes
Target IC₅₀: 280 nM inhibiting Src
Product competes with ATP.
Reversible: yes

警告

Toxicity: Irritant (B)

外形

A 10 mM (500 ?g/135 ?l) solution of SU6656 (Cat. No. 572635) in DMSO.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式	C19H21N3O3S
分子量	371.45

半岛bd体育手机客户端 性质

质量水平	100
测定	≥95% (HPLC)
形式	liquid
manufacturer/tradename	Calbiochem?
储存条件	OK to freeze desiccated (hygroscopic) protect from light
运输	wet ice
储存温度	2-8℃

安全信息

储存分类代码	10 - Combustible liquids
WGK	WGK 2
闪点(F)	188.6 °F - (Dimethylsulfoxide)
闪点(C)	87 ℃ - (Dimethylsulfoxide)