半岛bd体育手机客户端 名称:
H-
L
-Photo-Proline hydrochloride
Photo-crosslinking amino acid
(
S)-1,2,5-Triazaspiro[2.4]hept-1-ene-6-carboxylic acid
Photoprobe building block
Diazirine amino acid
Photo-Pro
半岛bd体育手机客户端 介绍:
半岛bd体育手机客户端 说明
应用
H-
L
-Photo-Proline HCl is a diazirine-containing proline amino acid and multifunctional probe building blocks. Its incorporation into peptides or small-molecule probes and tools allows for photoaffinity labeling of cellular targets and protein-protein interactions upon UV light (~360 nm) irradiation to form a covalent bond. This and other multifunctional probe building blocks will continue to accelerate drug discovery research for probing cellular mechanisms, target ID/validation, and understanding traditionally undruggable targets. An Fmoc-protected version is also available as 907324.
其他说明
Fishing for Drug Targets: A Focus on Diazirine Photoaffinity Probe Synthesis
Photo-affinity labeling (PAL) in chemical proteomics: a handy tool to investigate protein-protein interactions (PPIs)
基本信息
经验(实验)分子式 |
C5H8ClN3O2 |
分子量 |
177.59 |
半岛bd体育手机客户端 性质
测定 |
≥95% |
形式 |
powder |
reaction suitability |
reaction type: solution phase peptide synthesis |
application(s) |
peptide synthesis |
储存温度 |
?20℃ |
安全信息
储存分类代码 |
11 - Combustible Solids |
WGK |
WGK 3 |
闪点(F) |
Not applicable |
闪点(C) |
Not applicable |