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位置: 首页> 品牌> Sigma-Aldrich> Fmoc- L -photo-methionine

Fmoc- L -photo-methionine

品牌
Sigma-Aldrich
CAS
945859-89-2
货号
907367
包装型号
规格纯度
≥95%
价格
3382.37 *本价格含增值税费
促销
服务
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  • 增值税票
数量
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半岛bd体育手机客户端 名称:
945859-89-2
Fmoc- L -photo-methionine
Photo-crosslinking amino acid
( S)-2-(((9 H-Fluoren-9-yl)methoxy)carbonylamino)-4-(3-methyl-3 H-diazirin-3-yl)butanoic acid
Photoprobe building block
( S)-2-(Fmoc-amino)-4-(3 H-diazirin-3-yl)pentanoic acid
Photo-Met
Diazirine amino acid
半岛bd体育手机客户端 介绍:

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应用

Fmoc- L -photo-methionine is a diazirine-containing, Fmoc-protected methionine amino acid and multifunctional photo-crosslinker. Its incorporation into peptides or small-molecule probes and tools allows for photoaffinity labeling of cellular targets and protein-protein interactions upon UV light (~360 nm) irradiation to form a covalent bond. This and other multifunctional probe building blocks will continue to accelerate drug discovery research for probing cellular mechanisms, target ID/validation, and understanding traditionally undruggable targets. An unprotected version is also available as 907375.

其他说明

Developing diazirine-based chemical probes to identify histone modification ′readers′ and ′erasers ′

Proteome profiling reveals potential cellular targets of staurosporine using a clickable cell-permeable probe

Covalent Capture of Phospho-Dependent Protein Oligomerization by Site-Specific Incorporation of a Diazirine Photo-Cross-Linker

Fishing for Drug Targets: A Focus on Diazirine Photoaffinity Probe Synthesis

Photo-affinity labeling (PAL) in chemical proteomics: a handy tool to investigate protein-protein interactions (PPIs)

基本信息

经验(实验)分子式 C21H21N3O4
分子量 379.41

半岛bd体育手机客户端 性质

测定 ≥95%
形式 powder
reaction suitability reaction type: Fmoc solid-phase peptide synthesis
application(s) peptide synthesis
官能团 Fmoc
储存温度 ?20℃

安全信息

储存分类代码 11 - Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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