半岛bd体育手机客户端 说明
一般描述
A cell-permeable cationic surfactant that reversibly inhibits dynamin GTPase activity (IC50= 3.15 ?M) by targeting the PH domain and interfering with phospholipid binding. Shown to block dynamin I-dependent SVE (synaptic vesicle endocytosis) in rat brain synaptosomes and dynamin II-dependent RME (receptor-mediated endocytosis) in non-neuronal HeLa, A431, and COS-7 cells. Inhibition is competitive with respect to PS and noncompetitive with respect to GTP.
包装
500 mg in Glass bottle
Packaged under inert gas
警告
Toxicity: Corrosive (L)
重悬
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
其他说明
Quan, A., et al. 2007.Mol. Pharmacol.72,1425.
Hill, T.A., et al. 2004.Bioorg. Med. Chem. Lett.14,3275.
Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
| 经验(实验)分子式 | C17H38BrN |
| 分子量 | 336.39 |
| MDL编号 | MFCD00011770 |
半岛bd体育手机客户端 性质
| 质量水平 | 100 |
| 测定 | ≥99% (titration) |
| 形式 | solid |
| manufacturer/tradename | Calbiochem? |
| 储存条件 | OK to freeze desiccated (hygroscopic) |
| 颜色 | white |
| 溶解性 | DMSO: 10 mg/mL water: 100 mg/mL |
| 运输 | ambient |
| 储存温度 | 2-8℃ |
| InChI | 1S/C17H38N.BrH/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18(2,3)4;/h5-17H2,1-4H3;1H/q+1;/p-1 |
| InChI key | CXRFDZFCGOPDTD-UHFFFAOYSA-M |
安全信息
| 象形图 |     |
| 警示用语： | Danger |
| 危险声明 | H302 - H315 - H318 - H335 - H373 - H400 |
| 预防措施声明 | P273 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338 - P314 |
| 危险分类 | Acute Tox. 4 Oral - Aquatic Acute 1 - Eye Dam. 1 - Skin Irrit. 2 - STOT RE 2 Oral - STOT SE 3 |
| 靶器官 | Gastrointestinal tract, Respiratory system |
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
