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DIDS, Disodium Salt-CAS 53005-05-3-Calbiochem

二钠盐-CAS 53005-05-3-Calbiochem

品牌
Sigma-Aldrich
CAS
53005-05-3
货号
309795
规格纯度
Binds covalently and irreversibly to the outer surface of human erythrocyte membranes.
价格
2425.45 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
53005-05-3
DIDS, Disodium Salt-CAS 53005-05-3-Calbiochem
4,4'-Diisothiocyanostilbene-2,2'-disulfonic Acid, 2Na
二钠盐-CAS 53005-05-3-Calbiochem
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Binds covalently and irreversibly to the outer surface of human erythrocyte membranes. Inhibits ATP transport into endoplasmic reticulum vesicles. Anion transport inhibitor that inhibits Cluptake (IC50= 150 nM) in neuroblastoma cells. Has anti-ulcerous properties.
Binds covalently and irreversibly to the outer surface of human erythrocyte membrane proteins. Inhibits ATP transport into the endoplasmic reticulum vesicles. Anion transport inhibitor that inhibits Cl-uptake (IC50= 150 nM) in neuroblastoma cells. Has antiulcerous activity.

包装

250 mg in Plastic ampoule

生化/生理作用

Primary Target
Cl- uptake
Target IC50: 150 nM inhibiting Cl- uptake in neuroblastoma cells
Product does not compete with ATP.
Reversible: no
Cell permeable: no

警告

Toxicity: Irritant (B)

其他说明

Bettendorff, L., et al. 1995.Biochem. Biophys. Res. Commun.207,375.
Horie, S., et al. 1993.Res. Commun. Chem. Pathol. Pharmacol.79,117.
Mayinger, P., and Meyer, D.I. 1993.EMBO J.12,659.
Catantchik, Z.I., and Rothstein, A. 1974.J. Membr. Biol.15,207.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式 C16H8N2O6S4· 2Na
分子量 498.48

半岛bd体育手机客户端 性质

质量水平 100
测定 ≥85% (TLC)
形式 solid
manufacturer/tradename Calbiochem?
储存条件 OK to freeze
desiccated
protect from light
颜色 yellow
溶解性 water: 0.5%
运输 ambient
储存温度 ?20℃
InChI 1S/C16H10N2O6S4/c19-27(20,21)15-7-13(17-9-25)5-3-11(15)1-2-12-4-6-14(18-10-26)8-16(12)28(22,23)24/h1-8H,(H,19,20,21)(H,22,23,24)/b2-1+
InChI key YSCNMFDFYJUPEF-OWOJBTEDSA-N

安全信息

储存分类代码 11 - Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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