半岛bd体育手机客户端 说明

一般描述

A skeletal muscle relaxant. Blocks intracellular calcium release from the sarcoplasmic reticulum during excitation-contraction coupling by binding to the ryanodine receptor. Blocks long-term depression and depotentiation.
A cell-permeable blocker of intracellular calcium release from the sarcoplasmic reticulum that acts by binding to the ryanodine receptor. Inhibits long-term depression and depotentiation of synaptic transmission. Has neuroprotective effects in cases of cerebral ischemia.

包装

100 mg in Plastic ampoule

生化/生理作用

Cell permeable: yes
Product does not compete with ATP.
Reversible: no
Primary Target
Ryanodine receptor

警告

Toxicity: Harmful (C)

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

其他说明

Wei, H., and Perry, D.C. 1996.J. Neurochem.67,2390.
O’Mara, S.M., et al. 1995.Neuroscience68,621.
Parness, J., and Palnitkar, S.S. 1995.J. Biol. Chem.270,18465.
Zhang, H., et al. 1995.Am. J. Physiol.269,H1874.
Hotchkiss, R.S., and Karl, I.E. 1994.Proc. Natl. Acad. Sci. USA91,3039.
Song, S.K., et al. 1994.Proc. Natl. Acad. Sci. USA91,3039.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式	C14H9N4O5· Na
分子量	336.23
MDL编号	MFCD00079130

半岛bd体育手机客户端 性质

质量水平	100
测定	≥95% (HPLC)
形式	solid
manufacturer/tradename	Calbiochem?
储存条件	OK to freeze desiccated (hygroscopic)
颜色	orange
溶解性	DMSO: 3 mg/mL aqueous base: soluble
运输	ambient
储存温度	10-30℃
InChI	1S/C14H10N4O5.Na/c19-13-8-17(14(20)16-13)15-7-11-5-6-12(23-11)9-1-3-10(4-2-9)18(21)22;/h1-7H,8H2,(H,16,19,20);/q;+1/p-1/b15-7+;
InChI key	KSRLIXGNPXAZHD-HAZZGOGXSA-M

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 2
闪点(F)	Not applicable
闪点(C)	Not applicable