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位置: 首页> 品牌> Sigma-Aldrich> Congo Red, High Purity-CAS 573-58-0-Calbiochem

Congo Red, High Purity-CAS 573-58-0-Calbiochem

品牌
Sigma-Aldrich
CAS
573-58-0
货号
234610
规格纯度
An amyloidophylic dye that specifically stains stacked β sheet aggregates.
价格
1272.64 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
573-58-0
Congo Red, High Purity-CAS 573-58-0-Calbiochem
3,3'-[(1,1'-Biphenyl)-4,4'-diylbis(azo)]bis(4-amino-1-naphthalenesulfonic Acid) 2Na
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

An amyloidophylic dye that specifically stains stacked β sheet aggregates. Useful for staining and visual detection of amyloid deposits. Does not bind to non-polymerized amyloid peptide. Inhibits the accumulation of the scrapie-associated, protease-resistant isoform of protein PrP without affecting the metabolism of the normal isoform. It is also shown to inhibit Pot1 Binding to Telomeric DNA.
An amyloidophylic dye that specifically stains stacked β sheet aggre-gates. Useful for staining and visual detection of amyloid deposits in nerve tissue. Binds to amyloid fibrils but not to non-polymerized amyloid peptide. Inhibits the accumulation of the scrapie-associated, protease-resistant isoform of protein PrP without affecting the normal isoform possibly through overstabilization of the conformation. It is also shown to inhibit Pot1 Binding to Telomeric DNA.

包装

500 mg in Glass bottle

生化/生理作用

Primary Target
An amyloidophylic dye that specifically stains stacked β sheet aggregates
Product does not compete with ATP.
Reversible: no
Cell permeable: no

警告

Toxicity: Standard Handling (A)

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at room temperature (20°C).

其他说明

Altschuler, S.E., et al. 2012.Biochemistrin press.
Khurana, R., et al. 2001.J. Biol. Chem.276,22715.
Fezoui, Y., et al. 2000.Amyloid7,166.
Fezoui, Y., et al. 2000.Nat. Struct. Biol.7,1095.
Kramport, M., et al. 2000.Chem. Biol.7,855.
Kuner, P., et al. 2000.J. Biol. Chem.275,1673.
Caspi, S., et al. 1998.J. Biol. Chem.273,3484.
Caughey, B., and Race, A.E. 1992.J. Neurochem.59,768.
Taylor, D.L., et al. 1974.J. Histochem. Cytochem.22,1105.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式 C32H22N6O6S2· 2Na
分子量 696.66
MDL编号 MFCD00004028

半岛bd体育手机客户端 性质

质量水平 100
测定 ≥75% dye basis
形式 crystalline solid
manufacturer/tradename Calbiochem?
储存条件 OK to freeze
protect from light
颜色 rust
溶解性 water: 10 mg/mL
ethanol: soluble
运输 ambient
储存温度 15-25℃
InChI 1S/C32H24N6O6S2.2Na/c33-31-25-7-3-1-5-23(25)29(45(39,40)41)17-27(31)37-35-21-13-9-19(10-14-21)20-11-15-22(16-12-20)36-38-28-18-30(46(42,43)44)24-6-2-4-8-26(24)32(28)34;;/h1-18H,33-34H2,(H,39,40,41)(H,42,43,44);;/q;2*+1/p-2
InChI key IQFVPQOLBLOTPF-UHFFFAOYSA-L

安全信息

象形图 GHS08
警示用语: Danger
危险声明 H350 - H361d
预防措施声明 P201 - P202 - P280 - P308 + P313 - P405 - P501
危险分类 Carc. 1B - Repr. 2
储存分类代码 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK WGK 3

Sigma-Aldrich

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