半岛bd体育手机客户端 说明
应用
Carboxylic acid-poly(ethylene glycol)-b-poly(ε-caprolactone) is a functionalized, amphiphilic, diblock copolymer composed of a hydrophilic PEGblockand a hydrophobic PCLblock. These biodegradable, biocompatible polymers can self-assemble to form nanoparticles, such as micelles and polymersomes, in both aqueous and non-aqueous media. Due to these properties, these polymers are widely used in polymeric nanoparticle formulation to achieve controlled and targeted delivery of therapeutic agents (e.g. APIs, genetic material, peptides, vaccines, and antibiotics). Additionally, well-defined nanoparticles with tunable size and properties can be prepared by altering the molecular weight ratios between hydrophilic and hydrophobic blocks, as well as by controlling formulation parameters. The carboxylic acid functional group on the PEG chain enables rapid and facile surface functionalization, allowing for these materials to be used in applications such as targeted drug delivery.
基本信息
| 线性分子式 | C3H5O3[C2H4O]n[C6H10O2]mH |
半岛bd体育手机客户端 性质
| 质量水平 | 100 |
| 形式 | powder or chunks |
| 分子量 | PCL average Mn5,000 (by NMR) PCL average Mn5,000 PEG average Mn2,000 (by NMR) PEG average Mn2,000 |
| 颜色 | white to beige |
| PDI | ≤1.3 (by GPC) |
| 储存温度 | ?20℃ |
| SMILES string | [H]OCCCCCC(OCCOCCC(O)=O)=O |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
