半岛bd体育手机客户端 说明
一般描述
A substrate analog inhibitor of β-secretase (BACE) that completely blocks proteolytic activity in solubilized membrane fractions of BACE-transfected MDCK cells at a concentration of 5 ?M.
A substrate analog inhibitor of β-secretase (BACE) that completely blocks the proteolytic activity (at 5 ?M) in solubilized membrane fractions from BACE transfected MDCK cells.
包装
500 μg in Plastic ampoule
Packaged under inert gas
生化/生理作用
Product does not compete with ATP.
Primary Target
BACE
Reversible: no
Effective concentration: 5 ?M completely blocking the proteolytic activity of β-secretase (BACE) in solubilized membrane fractions from BACE transfected MDCK cells
Cell permeable: no
警告
Toxicity: Standard Handling (A)
序列
H-Glu-Val-Asn-Statine-Val-Ala-Glu-Phe-NH?
外形
Supplied as a trifluoroacetate salt.
重悬
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
其他说明
Capell, A., et al. 2002.J. Biol. Chem.277,5637.
Tung, J.S., et al. 2002.J. Med. Chem.45,259.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
| 经验(实验)分子式 | C44H70N10O14 |
| 分子量 | 963.09 |
半岛bd体育手机客户端 性质
| 质量水平 | 100 |
| 测定 | ≥95% (HPLC) |
| 形式 | lyophilized |
| manufacturer/tradename | Calbiochem? |
| 储存条件 | OK to freeze desiccated (hygroscopic) |
| 溶解性 | DMSO: 1 mg/mL |
| 运输 | ambient |
| 储存温度 | ?20℃ |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
