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位置: 首页> 品牌> Sigma-Aldrich> Anti-SMAD6 (AB2) antibody produced in rabbit

Anti-SMAD6 (AB2) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
AV32690
规格纯度
IgG fraction of antiserum
价格
3311.54 *本价格含增值税费
促销
服务
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  • 增值税票
数量
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半岛bd体育手机客户端 名称:
Anti-SMAD6 (AB2) antibody produced in rabbit
Anti-SMAD family member 6
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

SMAD6 is a transcription factor that belongs to the SMAD family of proteins that regulate cell growth and development. Studies have reported that Smad6 inhibits TGF-β and BMP/Smad1 signaling.
Rabbit Anti-SMAD6 recognizes zebrafish, canine, bovine, human, mouse, rat, and chicken SMAD6.

免疫原

Synthetic peptide directed towards the N terminal region of human SMAD6

应用

Rabbit Anti-SMAD6 can be used for western blot applications at a concentration of 0.5-1.0μg/ml. It can also be used for IHC assays at 4-8μg/ml, using paraffin-embedded tissues.

生化/生理作用

SMAD6 (mothers against decapentaplegic homolog 6) is an antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members; has been shown to inhibit selectively BMP (bone morphogenetic proteins) signaling by competing with the co-SMAD SMAD4 for receptor-activated SMAD1. SMAD6 is an inhibitory SMAD (I-SMAD) or antagonistic SMAD.

序列

Synthetic peptide located within the following region: APRDASDPLAGAALEPAGGGRSREARSRLLLLEQELKTVTYSLLKR

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
偶联物 unconjugated
抗体形式 IgG fraction of antiserum
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 53 kDa
species reactivity mouse, rat, dog, pig, human, bovine
浓度 0.5 mg - 1 mg/mL
technique(s) immunohistochemistry: suitable
western blot: suitable
NCBI登记号 NP_001136333
UniProt登记号 O43541
运输 wet ice
储存温度 ?20℃
Gene Information human ... SMAD6(4091)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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