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位置: 首页> 品牌> Sigma-Aldrich> Anti-SIN3B (AB1) antibody produced in rabbit

Anti-SIN3B (AB1) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
AV50589
规格纯度
affinity isolated antibody
价格
6889.23 *本价格含增值税费
促销
服务
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  • 增值税票
数量
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半岛bd体育手机客户端 名称:
Anti-SIN3B (AB1) antibody produced in rabbit
Anti-SIN3 homolog B, transcription Regulator (yeast)
Anti-KIAA0700
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

SIN3B codes for SIN3 transcription regulator family member B that interacts with Mad1. It is also known to form a nucleolar complex with leukemia associated ETO homologs.
Rabbit Anti-SIN3B antibody recognizes human, bovine, and mouse SIN3B.

免疫原

Synthetic peptide directed towards the middle region of human SIN3B

应用

Rabbit Anti-SIN3B antibody is suitable for western blot applications at a concentration of 1μg/ml.

生化/生理作用

SIN3B acts as a transcriptional repressor. It interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities.It also interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. SIN3B also forms a complex with FOXK1 which represses transcription.

序列

Synthetic peptide located within the following region: NDTKALRSKSLLNEIESVYDEHQEQHSEGRSAPSSEPHLIFVYEDRQILE

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 133 kDa
species reactivity bovine, pig, human, mouse, dog
浓度 0.5 mg - 1 mg/mL
technique(s) western blot: suitable
NCBI登记号 NP_056075
UniProt登记号 O75182
运输 wet ice
储存温度 ?20℃
Gene Information human ... SIN3B(23309)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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