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位置: 首页> 品牌> Sigma-Aldrich> 抗-NR2F2 (AB2) 兔抗

Anti-NR2F2 (AB2) antibody produced in rabbit

抗-NR2F2 (AB2) 兔抗

品牌
Sigma-Aldrich
货号
AV39465
规格纯度
IgG fraction of antiserum
价格
3617.94 *本价格含增值税费
促销
服务
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  • 包邮
  • 增值税票
数量
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半岛bd体育手机客户端 名称:
Anti-NR2F2 (AB2) antibody produced in rabbit
Anti-MGC117452
Anti-SVP40
Anti-ARP1
Anti-COUP-TFII
Anti-COUPTFB
Anti-TFCOUP2
Anti-Nuclear receptor subfamily 2, group F, member 2
抗-NR2F2 (AB2) 兔抗
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

NR2F2 codes for a steroid hormone receptor that is involved in the differentiation of human stem cells and trophoblasts. Genetic variations in NR2F2 are associated with congenital cardiac disorders.
Rabbit Anti-NR2F2 antibody recognizes human, mouse, rat, zebrafish, canine, bovine, and chicken NR2F2.

免疫原

Synthetic peptide directed towards the N terminal region of human NR2F2

应用

Rabbit Anti-NR2F2 antibody is suitable for western blot (2.5 μg/ml) and IHC (4-8 μg/ml) applications.

生化/生理作用

NR2F2, an orphan member of the nuclear hormone receptor superfamily, acts as a transcriptional repressor by antagonizing the functions of other nuclear hormone receptors and by actively silencing transcription. However, in certain contexts, NR2F2 stimulates transcription directly. NR2F2, MyoD and p300 interact in a competitive manner, and that increasing amounts of NR2F2 have the ability to reduce the interaction between myoD and p300 invitro. NR2F2 post-transcriptionally regulates myoD activity/function, and that crosstalk between orphan nuclear receptors and the myogenic bHLH proteins has functional consequences for differentiation.

序列

Synthetic peptide located within the following region: QDEVPGSQGSQASQAPPVPGPPPGAPHTPQTPGQGGPASTPAQTAAGGQG

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
偶联物 unconjugated
抗体形式 IgG fraction of antiserum
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 45 kDa
species reactivity bovine, guinea pig, human, mouse, rat, dog
浓度 0.5 mg - 1 mg/mL
technique(s) immunohistochemistry: suitable
western blot: suitable
NCBI登记号 NP_066285
UniProt登记号 P24468
运输 wet ice
储存温度 ?20℃
Gene Information human ... NR2F2(7026)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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