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Anti-KCNK3 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
AV35090
规格纯度
IgG fraction of antiserum
价格
3311.54 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
Anti-KCNK3 antibody produced in rabbit
Anti-Potassium channel, subfamily K, member 3
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

KCNK3 (TASK1) is a potassium channel protein that contains pore-forming domains. ML365 is known to selectively inhibit KCNK3. It is involved in the chemosensory regulation of breathing. KCNK3 variations have been linked to BP and aldosterone production.
Rabbit Anti-KCNK3 antibody recognizes human, mouse, rat, bovine, canine, and rabbit KCNK3.

免疫原

Synthetic peptide directed towards the C terminal region of human KCNK3

应用

Rabbit Anti-KCNK3 antibody is suitable for western blot applications at a concentration of 1.25 μg/ml.

生化/生理作用

KCNK3 encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The gene product is an outwardly rectifying channel that is sensitive to changes in extracellular pH and is inhibited by extracellular acidification. Also referred to as an acid-sensitive potassium channel, it is activated by the anesthetics halothane and isoflurane. Although three transcripts are detected in northern blots, there is currently no sequence available to confirm transcript variants for this gene.

序列

Synthetic peptide located within the following region: TCVEQSHSSPGGGGRYSDTPSRRCLCSGAPRSAISSVSTGLHSLSTFRGL

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
偶联物 unconjugated
抗体形式 IgG fraction of antiserum
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 43 kDa
species reactivity human, guinea pig, mouse, sheep, bovine, dog, rat
浓度 0.5 mg - 1 mg/mL
technique(s) western blot: suitable
NCBI登记号 NP_002237
UniProt登记号 O14649
运输 wet ice
储存温度 ?20℃
Gene Information human ... KCNK3(3777)

安全信息

储存分类代码 10 - Combustible liquids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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