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位置: 首页> 品牌> Sigma-Aldrich> Anti-CALR (AB1) antibody produced in rabbit

Anti-CALR (AB1) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
AV30114
规格纯度
affinity isolated antibody
价格
6305.78 *本价格含增值税费
促销
服务
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  • 增值税票
数量
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半岛bd体育手机客户端 名称:
Anti-CALR (AB1) antibody produced in rabbit
Anti-calreticulin
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Calreticulin (CALR) is a calcium-binding protein that can regulate nuclear hormone receptor-mediated gene transcription. CALR is also involved in integrin-mediated calcium signaling pathways and cell adhesion.
Rabbit Anti-CALR antibody recognizes human, mouse, rat, canine, rabbit, and pig calreticulin.

免疫原

Synthetic peptide directed towards the C terminal region of human CALR

应用

Rabbit Anti-CALR (AB1) antibody can be used for western blot (1.0μg/ml) applications.

生化/生理作用

Calreticulin is a multifunctional protein that acts as a major Ca(2+)-binding (storage) protein in the lumen of the endoplasmic reticulum. It is also found in the nucleus, suggesting that it may have a role in transcription regulation. Calreticulin binds to the synthetic peptide KLGFFKR, which is almost identical to an amino acid sequence in the DNA-binding domain of the superfamily of nuclear receptors. Calreticulin binds to antibodies in certain sera of systemic lupus and Sjogren patients which contain anti-Ro/SSA antibodies, it is highly conserved among species, and it is located in the endoplasmic and sarcoplasmic reticulum where it may bind calcium.

序列

Synthetic peptide located within the following region: FGNETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDK

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 48 kDa
species reactivity human, mouse, guinea pig, rat, horse, dog
浓度 0.5 mg - 1 mg/mL
technique(s) immunohistochemistry: suitable
western blot: suitable
NCBI登记号 NP_004334
UniProt登记号 P27797
运输 wet ice
储存温度 ?20℃
Gene Information human ... CALR(811)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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