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位置: 首页> 品牌> Sigma-Aldrich> 2-(Piperidin-4-yl)benzoic acid hydrochloride

2-(Piperidin-4-yl)benzoic acid hydrochloride

品牌
Sigma-Aldrich
CAS
1955554-64-9
货号
916854
包装型号
规格纯度
95%
价格
2018.33 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
1955554-64-9
2-(Piperidin-4-yl)benzoic acid hydrochloride
Semi-flexible linker for PROTAC development
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

应用

2-(Piperidin-4-yl)benzoic acid hydrochloride is a 4-aryl piperidine useful as a semi-flexible linker in PROTAC development for targeted protein degradation. Incorporation of rigidity into the linker region of bifunctional protein degraders may impact the 3D orientation of the degrader and thus ternary complex formation as well as optimization of drug-like properties.

其他说明

Portal: Building PROTAC?Degraders for Targeted Protein Degradation

Crosslinkers for Bioconjugation

Technology Spotlight: Degrader Building Blocks for Targeted Protein Degradation

法律信息

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

基本信息

经验(实验)分子式 C12H16ClNO2
分子量 241.71
MDL编号 MFCD08460728

半岛bd体育手机客户端 性质

质量水平 100
测定 95%
形式 powder
储存温度 2-8℃
SMILES string O=C(C1=C(C2CCNCC2)C=CC=C1)O.Cl
O=C(C1=C(C2CCNCC2)C=CC=C1)O.Cl

安全信息

储存分类代码 11 - Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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