2-(2-(Piperidin-4-yl)phenyl)ethan-1-amine dihydrochloride

半岛bd体育手机客户端 说明

应用

2-(2-(Piperidin-4-yl)phenyl)ethan-1-amine dihydrochloride is a 4-aryl piperidine useful as a semi-flexible linker in PROTAC development for targeted protein degradation. Incorporation of rigidity into the linker region of bifunctional protein degraders may impact the 3D orientation of the degrader and thus ternary complex formation as well as optimization of drug-like properties.

其他说明

Portal: Building PROTAC^?Degraders for Targeted Protein Degradation

Crosslinkers for Bioconjugation

Technology Spotlight: Degrader Building Blocks for Targeted Protein Degradation

法律信息

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

基本信息

经验(实验)分子式	C13H22Cl2N2
分子量	277.23

半岛bd体育手机客户端 性质

形式	powder
质量水平	100
储存温度	2-8℃
SMILES string	NCCC1=C(C=CC=C1)C2CCNCC2.Cl.Cl NCCC1=C(C=CC=C1)C2CCNCC2.Cl.Cl

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable