trans-Retinoic Acid-CAS 302-79-4-Calbiochem

半岛bd体育手机客户端 说明

一般描述

Potent modulator of growth and differentiation. Exerts its effects by binding to nuclear retinoic acid receptors (RARs) which directly regulate gene expression. Inhibits melanocyte adhesion, motility, and growth. Has keratolytic activity. Induces differentiation of tumor cells of neural origin. Induces apoptosis in acute promyelocytic carcinoma cells.
Potent modulator of growth and differentiation. Exerts its effects by binding to nuclear retinoic acid receptors (RARs) which directly regulate gene expression. Inhibits melanocyte adhesion, motility, and growth. Has keratolytic activity. Induces differentiation of tumor cells of neural origin. Induces apoptosis in acute promyelocytic carcinoma cells. PROTECT FROM AIR.

包装

500 mg in Glass bottle
Packaged under inert gas

警告

Toxicity: Harmful & Carcinogenic / Teratogenic (E)

重悬

Following reconstitution, store in the refrigerator (4°C). DMSO stock solutions are stable for up to 2 weeks at 4°C.

其他说明

Tosi, P., et al. 1994.Leuk. Lymphoma14,503.
Clagett-Dame, M., et al. 1993.Arch. Biochem. Biophys.300,684.
Labbaye, C., et al. 1993.Blood81,475.
Sakashita, A., et al. 1993.Blood81,1009.
Situ, R., et al. 1993.Dermatology186,38.
Tini, M., et al. 1993.Genes Develop.7,295.
Leid, M., et al. 1992.Trends Biochem. Sci.17,427.
Sharpe, C.R. 1991.Neuron7,239.
Thaller, C. and Eichele, G. 1990.Nature345,815.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式	C20H28O2
分子量	300.44
MDL编号	MFCD00001551

半岛bd体育手机客户端 性质

质量水平	100
测定	≥95% (by assay)
形式	solid
manufacturer/tradename	Calbiochem?
储存条件	OK to freeze desiccated (hygroscopic) protect from light
颜色	yellow
溶解性	DMSO: 25 mg/mL
运输	ambient
储存温度	2-8℃
InChI	1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14+
InChI key	SHGAZHPCJJPHSC-YCNIQYBTSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H302 - H315
预防措施声明	P264 - P270 - P280 - P301 + P312 - P302 + P352 - P332 + P313
危险分类	Acute Tox. 4 Oral - Skin Irrit. 2
储存分类代码	11 - Combustible Solids
WGK	WGK 2
闪点(F)	Not applicable
闪点(C)	Not applicable