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VTCN1 human

品牌
Sigma-Aldrich
货号
SRP6418
规格纯度
recombinant, expressed in HEK 293 cells, ≥90% (SDS-PAGE)
价格
3563.77 *本价格含增值税费
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数量
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半岛bd体育手机客户端 名称:
VTCN1 human
B7-H4
B7S1
B7h.5
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

V-set domain-containing T-cell activation inhibitor 1 (VTCN1) is also known as Immune costimulatory protein B7-H4, Protein B7S1, T-cell costimulatory molecule B7x, B7H4, which belongs to the immunoglobulin superfamily and BTN/MOG family. VTCN1 contains two Ig-like V-type (immunoglobulin-like) domains. The expression of VTCN1 is up-regulated by IL6 and IL10 and is inhibited by GM-CSF and IL4 on antigen-presenting cells (APCs). VTCN1 / B7-H4 negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. VTCN1 involved in promoting epithelial cell transformation.

外形

Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Generally 5-8% Mannitol or trehalose is added as a protectant before lyophilization.

重悬

Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 μg/mL. Do not vortex. This solution can be stored at 2-8℃ for up to 1 month. For extended storage, it is recommended to store at -20℃.

基本信息

NACRES NA.32

半岛bd体育手机客户端 性质

生物来源 human
重组 expressed in HEK 293 cells
标签 6-His tagged (C-terminus)
测定 ≥90% (SDS-PAGE)
形式 lyophilized
分子量 calculated mol wt 26.1 kDa
observed mol wt 45-60 kDa (DTT-reduced. Protein migrates due to glycosylation. Phe 29 is the predicted N-terminal.)
包装 pkg of 10 μg
pkg of 50 μg
UniProt登记号 Q7Z7D3
运输 wet ice
储存温度 ?20℃
Gene Information human ... VTCN1(79679)

安全信息

储存分类代码 11 - Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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