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ULBP1 human

品牌
Sigma-Aldrich
货号
SRP6347
规格纯度
recombinant, expressed inE. coli, ≥90% (SDS-PAGE)
价格
6021.17 *本价格含增值税费
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数量
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半岛bd体育手机客户端 名称:
ULBP1 human
N2DL-1
RAET1I
UL16 binding protein 1
NKG2D ligand 1
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

ULBP1 is ligand for the NKG2D receptor, together with at least ULBP2 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. In CMV infected cells, ULBP1 interacts with soluble CMV glycoprotein UL16. The interaction with UL16 blocked the interaction with the NKG2D receptor, providing a mechanism by which CMV infected cells might escape the immune system. UL16 also causes ULBP1 to be retained in the ER and cis-Golgi apparatus so that it does not reach the cell surface. Recombinant human ULBP1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

外形

0.5 mg/mL in 20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 30% glycerol and 1 mM DTT.

基本信息

NACRES NA.32

半岛bd体育手机客户端 性质

生物来源 human
重组 expressed inE. coli
测定 ≥90% (SDS-PAGE)
形式 liquid
分子量 25 kDa (216 aa, 26-216 aa + His Tag)
包装 pkg of 100 μg
浓度 0.5 mg/mL
UniProt登记号 Q9BZM6
运输 dry ice
储存温度 ?70℃
Gene Information human ... ULBP1(80329)

安全信息

象形图 GHS07
警示用语: Warning
危险声明 H319
预防措施声明 P264 - P280 - P305 + P351 + P338 - P337 + P313
危险分类 Eye Irrit. 2
储存分类代码 11 - Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

Sigma-Aldrich

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