(1 S ,2 S ,3 R ,5 S )-3-[7-{[(1 R ,2 S )-2-（3,4-二氟苯基）环丙基] 氨基 }-5-（丙基砜基）-3 H - [1,2,3] 三唑 [4,5- d 嘧啶-3-基]-5-（2-羟乙氧基）-1,2-环戊二醇

替格瑞洛

品牌

Sigma-Aldrich

CAS

274693-27-5

货号

SML2482

包装型号

规格纯度

≥98% (HPLC)

价格

742.66 元 *本价格含增值税费

促销

数量

- +

半岛bd体育手机客户端名称：

274693-27-5
Ticagrelor
(1 S,2 S,3 R,5 S)-3-[7-{[(1 R,2 S)-2-(3,4-Difluorophenyl)cyclopropyl]amino}-5-(propylsulfanyl)-3 H-[1,2,3]triazolo[4,5- d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-1,2-cyclopentanediol
(1S,2S,3R,5S)-3-[7-{[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]amino}-5-(propylthio)-3H-[1,2,3]-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
替格瑞洛
(1 S,2 S,3 R,5 S)-3-[7-{[(1 R,2 S)-2-（3,4-二氟苯基）环丙基] 氨基 }-5-（丙基砜基）-3 H- [1,2,3] 三唑 [4,5- d嘧啶-3-基]-5-（2-羟乙氧基）-1,2-环戊二醇

半岛bd体育手机客户端介绍：

半岛bd体育手机客户端说明

一般描述

Ticagrelor (AZD6140) is a cyclopentyl-triazolopyrimidine.

生化/生理作用

Ticagrelor is an antithrombotic antiplatelet drug that acts by direct and reversible competitive inhibition of the adensoine purinoceptor P2Y12 receptor. It has clinical benefits in people affected with acute coronary syndrome. It might also play a beneficial role on endothelial function. Ticagrelor can prevent the uptake of adenosine by human erythrocytes and can promote the liberation of adenosine triphosphate (ATP) from human erythrocytes.

基本信息

经验(实验)分子式	C₂₃H₂₈F₂N₆O₄S
分子量	522.57
MDL编号	MFCD09954148

半岛bd体育手机客户端性质

测定	≥98% (HPLC)
形式	powder
旋光性	[α]/D -55 to -65°, c = 0.2 in methanol
颜色	white to beige
溶解性	DMSO: 2 mg/mL, clear
储存温度	?20℃
SMILES string	CCCSC1=NC(N[C@@]2([H])[C@@](C3=CC=C(F)C(F)=C3)([H])C2)=C4C(N([C@@]5([H])[C@H](O)[C@H](O)[C@@H](OCCO)C5)N=N4)=N1
InChI	1S/C23H28F2N6O4S/c1-2-7-36-23-27-21(26-15-9-12(15)11-3-4-13(24)14(25)8-11)18-22(28-23)31(30-29-18)16-10-17(35-6-5-32)20(34)19(16)33/h3-4,8,12,15-17,19-20,32-34H,2,5-7,9-10H2,1H3,(H,26,27,28)/t12-,15+,16+,17-,19-,20+/m0/s1
InChI key	OEKWJQXRCDYSHL-FNOIDJSQSA-N
Gene Information	human ... P2RY12(64805)

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable