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TGFβR1 (80-end), GST tagged human

品牌
Sigma-Aldrich
CAS
186709-18-2
货号
SRP5145
规格纯度
recombinant, expressed in baculovirus infectedSf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
价格
4311.28 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
186709-18-2
TGFβR1 (80-end), GST tagged human
AAT5
ALK-5
ALK5
SKR4
ACVRLK4
TGFR-1
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

TGFβR1 is a transmembrane serine/threonine protein kinase and a member of the TGFβ receptor subfamily. TGFβ regulates cell cycle progression by a unique signaling mechanism that involves its binding to TGFβR2 and activation of TGFβR1. TGFβR1 may be inactivated in many of the cases of human tumor cells refractory to TGFβ-mediated cell cycle arrest. Heterozygous mutations in TGFβR1 and TGFβR2 have been reported in Loeys-Dietz aortic aneurysm syndrome (LDS) and also dominant TGFβR2 mutations have been identified in Marfan syndrome type 2 (MFS2) and familial thoracic aortic aneurysms and dissections (TAAD). Mutations of TGFβR1 and TGFβR2 are associated with atherosclerosis and several human cancers.

外形

Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.

制备说明

after opening, aliquot into smaller quantities and store at -70 ℃. Avoid repeating handling and multiple freeze/thaw cycles

基本信息

NACRES NA.32

半岛bd体育手机客户端 性质

生物来源 human
重组 expressed in baculovirus infectedSf9 cells
测定 ≥70% (SDS-PAGE)
形式 buffered aqueous glycerol solution
分子量 ~65 kDa
NCBI登记号 BC071181
application(s) cell analysis
运输 dry ice
储存温度 ?70℃
Gene Information human ... TGFBR1(7046)

安全信息

储存分类代码 10 - Combustible liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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