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TFIIH, p62 subunit human

品牌
Sigma-Aldrich
货号
SRP2011
规格纯度
recombinant, expressed inE. coli, ≥70% (SDS-PAGE)
价格
5369.18 *本价格含增值税费
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数量
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半岛bd体育手机客户端 名称:
TFIIH, p62 subunit human
BTF2
TFIIH
TFB1
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

生化/生理作用

TFIIH, a multi-subunit complex is involved in several biological fundamental mechanisms of the cell: transcription, nucleotide excision repair and cell cycle regulation. p62 is one of the six subunits that constitutes the core of TFIIH. Analysis of the expression of the p62 gene reveals an over-expression in testis tissue. This subunit of TFIIH participates in a variety of protein-protein interactions. For example, Rb competes with TBP and p62 for binding to E2F thus repressing E2F-mediated trans-activation; herpes simplex virus VP16 and human p53 directly interact with the p62 subunit of TFIIH. In addition, TFIIH, via p62 phosphorylation is the major target for mitotic inactivation of transcription.

外形

Clear and colorless frozen liquid solution

制备说明

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. While working, please keep sample on ice.

基本信息

NACRES NA.26

半岛bd体育手机客户端 性质

生物来源 human
重组 expressed inE. coli
测定 ≥70% (SDS-PAGE)
形式 frozen liquid
分子量 ~64.4 kDa
包装 pkg of 10 μg
储存条件 avoid repeated freeze/thaw cycles
浓度 750 μg/mL
颜色 clear colorless
NCBI登记号 NM_005316
UniProt登记号 P32780
运输 dry ice
储存温度 ?70℃
Gene Information human ... GTF2H1(2965)

安全信息

储存分类代码 10 - Combustible liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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