半岛bd体育手机客户端 说明
应用
Useful for kinase assay and Western blot.
生化/生理作用
Recombinant full-length human tag-free Tau-316 was expressed inE. colicells. Tau-316 encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. Tau-316 transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type(1). Tau-316 gene mutations have been associated with several neurodegenerative disorders such as Alzheimer′s disease, Pick′s disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy(2).
序列
Full Length
重悬
Formulated in 50mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM PMSF, with 25% glycerol.
储存及稳定性
Store in aliquots at -70℃. Avoid freeze/thaw cycles.
半岛bd体育手机客户端 性质
重组 | expressed inE. coli |
测定 | 70-95% (SDS-PAGE) |
形式 | frozen liquid |
分子量 | ~39 kDa |
浓度 | 0.2 μg/μL |
登记号 | P10636-3 |
运输 | dry ice |
储存温度 | ?70℃ |
Gene Information | human ... MAPT(4137) |
安全信息
储存分类代码 | 10 - Combustible liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich