半岛bd体育手机客户端 说明
一般描述
SOD1 (superoxide dismutase 1) is the major soluble cytoplasmic enzyme responsible for destroying harmful free superoxide radicals in the body thereby providing defence against oxygen free-radical toxicity. Soluble cytoplasmic SOD1 is a copper- and zinc-containing enzyme and the SOD1 gene maps to chromosome 21q22. Mutations in the SOD1 gene have been implicated to be the cause of familial amyotrophic lateral sclerosis, increased age-related muscle mass loss, early development of cataracts, macular degeneration, thymic involution, hepatocellular carcinoma, and shortned lifespan.
外形
Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
制备说明
after opening, aliquot into smaller quantities and store at -70 ℃. Avoid repeating handling and multiple freeze/thaw cycles
基本信息
NACRES | NA.32 |
半岛bd体育手机客户端 性质
生物来源 | human |
重组 | expressed inE. coli |
测定 | ≥70% (SDS-PAGE) |
形式 | buffered aqueous glycerol solution |
分子量 | ~45 kDa |
NCBI登记号 | NM_000454 |
application(s) | cell analysis |
运输 | dry ice |
储存温度 | ?70℃ |
Gene Information | human ... SOD1(6647) |
安全信息
储存分类代码 | 10 - Combustible liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich