SBK1, Active

半岛bd体育手机客户端 说明

应用

Useful for kinase assay.

生化/生理作用

Full-length recombinant human SBK1 was expressed byBaculovirusin Sf9 insect cells using an N-terminal GST tag. SBKI or SH3 domain binding kinase 1 is a novel serine/threonine protein kinase structurally related to a Xenopus gastrula-specific protein kinase, Pk9.7 which possessing a consensus sequence for an SH3-binding domain from developing rat brain and it play an important role in signal-transduction pathways related to the control of brain development⁽¹⁾. SBK1 may predict a broad cellular function, and its dysregulated in certain cancers suggests an involvement of the protein in the pathogenesis of human cancers⁽²⁾.

重悬

Formulated in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, with 25% glycerol.

储存及稳定性

Store in aliquots at -70℃. Avoid freeze/thaw cycles.

法律信息

PRECISIO is a registered trademark of sigma-aldrich Co. LLC

半岛bd体育手机客户端 性质

重组	expressed in baculovirus infectedSf9 cells
测定	0.05-0.1 μg/μL 70-95% (SDS-PAGE)
形式	frozen liquid
specific activity	15-25 nmol/min·mg (radiometric)
分子量	~69 kDa
登记号	NM_001024401
运输	dry ice
储存温度	?70℃
Gene Information	human ... SBK1(388228)

安全信息

储存分类代码	10 - Combustible liquids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable