半岛bd体育手机客户端 说明
应用
Salsalate was used to study the effect on palmitate-induced insulin resistance and hepatic steatosis in obese rats.
包装
50, 250 mg in glass bottle
生化/生理作用
Salsalate is a nonsteroidal anti-inflammatory drug (NSAID), a nonacetylated salicylate with no more problems of gastrointestinal bleeding than placebo. It inhibits synthesis and release of prostaglandins through the inactivation of cyclooxygenase-1 (COX-1) and COX-2. Salsalate is currently being investigated as a treatment for Type 2 diabetes with possible use to prevent the disease in people at risk. It reduces blood glucose concentrations in patients with type 2 diabetes, as well as in insulin-resistant patients without diabetes.
基本信息
| 经验(实验)分子式 | C14H10O5 |
| 分子量 | 258.23 |
| EC 号 | 209-027-4 |
| MDL编号 | MFCD00020252 |
| PubChem化学物质编号 | 329825134 |
| NACRES | NA.77 |
半岛bd体育手机客户端 性质
| 测定 | ≥98% (HPLC) |
| 形式 | powder |
| 颜色 | white to tan |
| 溶解性 | DMSO: ≥15 mg/mL |
| 储存温度 | room temp |
| SMILES string | OC(=O)c1ccccc1OC(=O)c2ccccc2O |
| InChI | 1S/C14H10O5/c15-11-7-3-1-5-9(11)14(18)19-12-8-4-2-6-10(12)13(16)17/h1-8,15H,(H,16,17) |
| InChI key | WVYADZUPLLSGPU-UHFFFAOYSA-N |
安全信息
| 象形图 |   |
| 警示用语： | Warning |
| 危险声明 | H302 - H400 |
| 预防措施声明 | P273 - P301 + P312 + P330 |
| 危险分类 | Acute Tox. 4 Oral - Aquatic Acute 1 |
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
