半岛bd体育手机客户端 说明
包装
10, 50 mg in glass bottle
生化/生理作用
Ralfinamide is a mixed sodium and N-type calcium channel blocker. Inhibiton is voltage-dependent, with higher potency against inactivated channels. Ralfinamide is two fold selective for tetrodotoxin (TTX)-resistant sodium channels compared with TTX-sensitive currents.
特点和优势
This compound is featured on the Calcium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
基本信息
经验(实验)分子式 | C17H19FN2O2· CH3SO3H |
分子量 | 398.45 |
MDL编号 | MFCD19690932 |
PubChem化学物质编号 | 329825378 |
NACRES | NA.77 |
半岛bd体育手机客户端 性质
测定 | ≥98% (HPLC) |
形式 | powder |
旋光性 | [α]/D 10 to 15° (c=1 HOAc) |
颜色 | white to beige |
溶解性 | H2O: >15 mg/mL |
储存温度 | 2-8℃ |
SMILES string | CS(O)(=O)=O.C[C@H](NCc1ccc(OCc2ccccc2F)cc1)C(N)=O |
InChI | 1S/C17H19FN2O2.CH4O3S/c1-12(17(19)21)20-10-13-6-8-15(9-7-13)22-11-14-4-2-3-5-16(14)18;1-5(2,3)4/h2-9,12,20H,10-11H2,1H3,(H2,19,21);1H3,(H,2,3,4)/t12-;/m0./s1 |
InChI key | CHQVNINIGBRKGZ-YDALLXLXSA-N |
安全信息
象形图 | |
警示用语: | Danger |
危险声明 | H301 |
预防措施声明 | P301 + P310 |
危险分类 | Acute Tox. 3 Oral |
储存分类代码 | 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich