半岛bd体育手机客户端 说明
免疫原
The epitope recognized by PLA0132 maps to a region between residue 700 and the C-terminus (residue 747) of human Silent Mating Type Information Regulation 2 homolog 1 using the numbering given in entry NP_036370.2 (GeneID 23411).
外形
Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide
其他说明
Sirt1 is one of seven members of the sirtuin family of proteins that are homologous to the yeast silent information regulator 2 (Sir2), a NAD÷-dependent protein deacetylase that plays a role in lifespan in lower eukaryotes. The sirtuins are diverse in their cellular functions, and are important to the regulation of oxidative stress, and metabolism. Sirt 1 is localized to the nucleus and possesses deacetylase activity. Sirt 1 has been shown to be able to deacetylate p53, Ku70, NF-kappaB and forkhead proteins to mediate cellular resistance to stress.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
NACRES | NA.41 |
半岛bd体育手机客户端 性质
生物来源 | rabbit |
质量水平 | 100 |
抗体形式 | affinity purified immunoglobulin |
antibody product type | primary antibodies |
等级 | Powered by Bethyl Laboratories, Inc. |
species reactivity | human |
technique(s) | immunoprecipitation (IP): 1-4 μg/mg western blot: 1:2,000- 1:10,000 |
登记号 | NP_036370.2 |
UniProt登记号 | Q96EB6 |
运输 | wet ice |
储存温度 | 2-8℃ |
Gene Information | rabbit ... Sirt1(23411) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich