半岛bd体育手机客户端 说明
一般描述
PIK3C2A is belongs to the phosphoinositide 3-kinase (PI3K) family which play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. PIK3C2A can phosphorylate phosphatidylinositol and phosphatidylinositol-4-phosphate in vitro. PIK3C2A contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases that act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions.
外形
Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
制备说明
After opening, aliquot into smaller quantities and store at -70 ℃. Avoid repeating handling and multiple freeze/thaw cycles.
法律信息
PRECISIO is a registered trademark of sigma-aldrich Co. LLC
基本信息
NACRES | NA.32 |
半岛bd体育手机客户端 性质
重组 | expressed in baculovirus infected Sf9 cells |
半岛bd体育手机客户端 线 | PRECISIO® |
测定 | ≥70% (SDS-PAGE) |
形式 | buffered aqueous glycerol solution |
specific activity | 16.2-25.3 nmol/min·mg |
分子量 | ~155 kDa |
NCBI登记号 | NM_002645 |
运输 | dry ice |
储存温度 | −70℃ |
Gene Information | human ... PIK3C2A(5286) |
安全信息
储存分类代码 | 10 - Combustible liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich