半岛bd体育手机客户端 说明

一般描述

PI3K phosphorylate the 3-prime OH position of the inositol ring of inositol lipids which functions in signaling pathways that regulate cell growth by virtue of their activation in response to various mitogenic stimuli. PI3Ks are composed of a 110-kDa catalytic subunit and a 85-kDa adaptor subunit. PI3K plays a critical role in regulating the formation and stability of alpha-2B-beta-3 integrin adhesion bonds, which are necessary for shear force-induced platelet activation. PI3K sustains alpha-2B-beta-3 integrin activation and stabilized platelet aggregation by regulating both integrin-dependent calcium flux and Gi activation of RAP1B.

外形

Supplied in 50 mM sodium phosphate, pH 7.0, 300 mM NaCl, 150 mM imidazole, 0.1 mM PMSF, 0.2 mM DTT, 25% glycerol.

制备说明

After opening, aliquot into smaller quantities and store at -70 ℃. Avoid repeating handling and multiple freeze/thaw cycles.

法律信息

PRECISIO is a registered trademark of sigma-aldrich Co. LLC

基本信息

NACRES

NA.32

半岛bd体育手机客户端 性质

生物来源	human
重组	expressed in baculovirus infectedSf9 cells
半岛bd体育手机客户端 线	PRECISIO?
测定	≥70% (SDS-PAGE)
形式	buffered aqueous glycerol solution
specific activity	22.4-33.6 nmol/min·mg
分子量	~111 kDa (p110β) ~88 kDa (p85β)
NCBI登记号	NM_006219
application(s)	cell analysis
运输	dry ice
储存温度	?70℃
Gene Information	human ... PIK3CB(5291)

安全信息

象形图
警示用语：	Danger
危险声明	H315 - H319 - H360D
预防措施声明	P202 - P264 - P280 - P302 + P352 - P305 + P351 + P338 - P308 + P313
危险分类	Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2
储存分类代码	6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable