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PDE6A (31-end), active, GST tagged human

品牌
Sigma-Aldrich
货号
SRP5058
规格纯度
recombinant, expressed in baculovirus infectedSf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
价格
6885.71 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
PDE6A (31-end), active, GST tagged human
CGPR-A
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

PDE6A encodes the cyclic-GMP (cGMP)-specific phosphodiesterase 6A and is expressed in cells of the retinal rod outer segment. The phosphodiesterase 6 holoenzyme is a heterotrimer composed of an alpha, beta, and two gamma subunits. cGMP is an important regulator of rod cell membrane current, and its dynamic concentration is established by phosphodiesterase 6A cGMP hydrolysis and guanylate cyclase cGMP synthesis. The protein is a subunit of a key phototransduction enzyme and participates in processes of transmission and amplification of the visual signal. Mutations in this gene have been identified as one cause of autosomal recessive retinitis pigmentosa.

外形

Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.

制备说明

after opening, aliquot into smaller quantities and store at -70 ℃. Avoid repeating handling and multiple freeze/thaw cycles

基本信息

NACRES NA.32

半岛bd体育手机客户端 性质

重组 expressed in baculovirus infectedSf9 cells
测定 ≥70% (SDS-PAGE)
形式 buffered aqueous glycerol solution
specific activity 32-44 nmol/min·mg
分子量 ~120 kDa
NCBI登记号 NM_000440
运输 dry ice
储存温度 ?70℃
Gene Information human ... PDE6A(5145)

安全信息

储存分类代码 10 - Combustible liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

Sigma-Aldrich

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