半岛bd体育手机客户端 说明
生化/生理作用
Human PC4 is a non-TAF transcription coactivator that mediates activator-dependent transcription by RNA polymerase IIin vitrothrough most tested activators. The function of PC4 is through interactions with transcriptional activators and the basal transcription machinery. It is negatively regulated by casein kinase II phosphorylation bothin vitroandin vivo. PC4 strongly binds single stranded DNA and the region essential for the single stranded DNA binding activity was mapped around residue 77. A single amino acid change at position 77 (F to P) abolishes both ds- and ss-DNA binding activity.
外形
Clear and colorless frozen liquid solution
制备说明
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. While working, please keep sample on ice.
基本信息
| NACRES | NA.26 |
半岛bd体育手机客户端 性质
| 生物来源 | human |
| 重组 | expressed inE. coli |
| 测定 | ≥80% (SDS-PAGE) |
| 形式 | frozen liquid |
| 分子量 | ~14.4 kDa |
| 包装 | pkg of 10 μg |
| 浓度 | 1000 μg/mL |
| 颜色 | clear colorless |
| NCBI登记号 | NM_006713 |
| UniProt登记号 | P53999 |
| 运输 | dry ice |
| 储存温度 | ?70℃ |
| Gene Information | human ... SUB1(10923) |
安全信息
| 储存分类代码 | 10 - Combustible liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
