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位置: 首页> 品牌> Sigma-Aldrich> PA-824

PA-824

品牌
Sigma-Aldrich
CAS
187235-37-6
货号
SML1290
规格纯度
≥98% (HPLC)
价格
2991.98 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
- +
半岛bd体育手机客户端 名称:
187235-37-6
PA-824
(6S)-2-Nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine
PA 824
(6S)- 6,7-Dihydro-2-nitro-6-[[4-(trifluoromethoxy)phenyl]methoxy]-5H-Imidazo[2,1-b][1,3]oxazine
(S)-PA 824
Pretomanid
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

包装

10, 50 mg in glass bottle

生化/生理作用

PA-824 is an anti-tuberculosis drug.
PA-824 is a pro-drug that has an effect on both replicating and non-replicatingMycobacterium tuberculosis. It is activated by deazaflavin (cofactor F420)-dependent nitroreducase.
PA-824 is an anti-tuberculosis drug that exhibits multiple mechanism of action, including both cell wall inhibition and respiratory poisoning.

基本信息

经验(实验)分子式 C14H12F3N3O5
分子量 359.26
NACRES NA.77

半岛bd体育手机客户端 性质

质量水平 100
测定 ≥98% (HPLC)
形式 powder
旋光性 [α]/D -40 to -48°, c = 1 in methanol
颜色 white to brown
溶解性 DMSO: 5 mg/mL, clear (warmed)
储存温度 ?20℃
InChI 1S/C14H12F3N3O5/c15-14(16,17)25-10-3-1-9(2-4-10)7-23-11-5-19-6-12(20(21)22)18-13(19)24-8-11/h1-4,6,11H,5,7-8H2/t11-/m0/s1
InChI key ZLHZLMOSPGACSZ-NSHDSACASA-N

安全信息

象形图 GHS07
警示用语: Warning
危险声明 H315 - H319 - H335
预防措施声明 P280 - P304 + P340 + P312 - P305 + P351 + P338 - P337 + P313
危险分类 Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官 Respiratory system
储存分类代码 13 - Non Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

Sigma-Aldrich

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