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NMNAT3 human

品牌
Sigma-Aldrich
货号
SRP6531
规格纯度
recombinant, expressed inE. coli, ≥95% (SDS-PAGE)
价格
4791.37 *本价格含增值税费
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数量
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半岛bd体育手机客户端 名称:
NMNAT3 human
NaMN adenylyltransferase 3
EC 2.7.7.1
Nicotinamide Mononucleotide Adenylyl-transferase 3
NMN adenylyltransferase 3
EC 2.7.7.18
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

This is the Mitochondrial NMNAT isoform. It catalyzes the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. It can also use the deamidated form of nicotinic acid mononucleotide (NAMN) as substrate with the same efficiency. It can use tiazofurin monophosphate as substrate. It can also use GTP and ITP as nucleotide donors. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD+. For the pyrophosphorolytic activity, mitochondrial NMNAT isoform can use NAD (+), NADH, NAAD, nicotinic acid adenine dinucleotide phosphate (NHD), nicotinamide guanine dinucleotide (NGD) as substrates. It fails to cleave phosphorylated dinucleotides NADP+, NADPH and NAADP+. It protects against axonal degeneration following injury.

外形

1 mg/mL in 50 mM sodium phosphate, pH 8.0 containing 300 mM sodium chloride, 1 mM DTT and 10% glycerol.

基本信息

NACRES NA.32

半岛bd体育手机客户端 性质

生物来源 human
重组 expressed inE. coli
测定 ≥95% (SDS-PAGE)
形式 liquid
分子量 monomer ~270 kDa (Human full-length NMNAT3 aa 1-252 is fused at the N-terminus to a His-tag.)
包装 pkg of 10 and 50 μg
浓度 1 mg/mL
UniProt登记号 Q96T66
运输 wet ice
储存温度 ?20℃
Gene Information human ... NMNAT3(349565)

安全信息

储存分类代码 13 - Non Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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