半岛bd体育手机客户端 说明
包装
10, 50 mg in glass bottle
生化/生理作用
Nepafenac is a NSAID (nonsteroidal anti inflammatory drug) that is routinely used in opthamology to control pain following cataract surgery.
Nepafenac, a prodrug of amfenac, is used in the treatment of diabetic retinopathy. It is metabolized to its active form through intraocular enzymatic hydrolysis. Nepafenac has a molecular weight of 254.28 kDa and effectively penetrates through the cornea. Its molecule structure enables nepafenac to possess better permeability. Nepafenac has a low inhibitory effect on cyclooxygenase.
基本信息
经验(实验)分子式 | C15H14N2O2 |
分子量 | 254.28 |
MDL编号 | MFCD08067732 |
PubChem化学物质编号 | 329825296 |
NACRES | NA.77 |
半岛bd体育手机客户端 性质
测定 | ≥98% (HPLC) |
形式 | powder |
颜色 | faintly yellow to dark yellow |
溶解性 | DMSO: ≥5 mg/mL |
储存温度 | room temp |
SMILES string | NC(=O)Cc1cccc(c1N)C(=O)c2ccccc2 |
InChI | 1S/C15H14N2O2/c16-13(18)9-11-7-4-8-12(14(11)17)15(19)10-5-2-1-3-6-10/h1-8H,9,17H2,(H2,16,18) |
InChI key | QEFAQIPZVLVERP-UHFFFAOYSA-N |
Gene Information | human ... PTGS1(5742), PTGS2(5743) |
安全信息
象形图 | |
警示用语: | Warning |
危险声明 | H400 |
预防措施声明 | P273 |
危险分类 | Aquatic Acute 1 |
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich