半岛bd体育手机客户端 说明
生化/生理作用
Nedaplatin is a second-generation cisplatin analog with antineoplastic activity. Containing a novel ring structure in which glycolate is bound to the platinum by a bidentate ligand, nedaplatin forms reactive platinum complexes that bind to nucelophillic groups in DNA, resulting in intrastrand and interstrand DNA cross-links, apoptosis and cell death. Nedplatin is less nephrotoxic and neurotoxic compared to both cisplatin and carboplatin.
基本信息
| 经验(实验)分子式 | C2H8N2O3Pt |
| 分子量 | 303.17 |
半岛bd体育手机客户端 性质
| 形式 | powder |
| 储存温度 | 2-8℃ |
| InChI | 1S/C2H4O3.2H2N.Pt/c3-1-2(4)5;;;/h3H,1H2,(H,4,5);2*1H2;/q;2*-1;+2 |
| InChI key | KLNFSAOEKUDMFA-UHFFFAOYSA-N |
安全信息
| 象形图 |   |
| 警示用语： | Danger |
| 危险声明 | H300 - H315 - H317 - H319 - H334 - H335 - H350 |
| 预防措施声明 | P201 - P261 - P280 - P301 + P310 + P330 - P304 + P340 + P312 - P308 + P313 |
| 危险分类 | Acute Tox. 2 Oral - Carc. 1B - Eye Irrit. 2 - Resp. Sens. 1B - Skin Irrit. 2 - Skin Sens. 1B - STOT SE 3 |
| 靶器官 | Respiratory system |
| 储存分类代码 | 6.1B - Non-combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
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